案例信息
标题:破解菌群“得失利弊”,促进肠-肝“和合双全”——肠道菌群稳态与肝脏健康案例分析
【专业学位类别】 公共卫生
【专业领域/方向】卫生毒理学
【作者】 林忠宁
【单位】 厦门大学公共卫生杏鑫娱乐
【关键词】肝脏、肠道菌群、肠-肝串扰、公共卫生/医疗干预策略、研究与实践
【适用课程】卫生毒理学
【版权说明】仅用于教学目的
【案例摘要】
研究和开发调节肝脏健康的公共卫生/医疗指导或干预策略,助力流行性疾病的社会性预防控制和治疗已成为当前公卫医学研究领域亟待解决的关键学科问题之一。近几年随着对肠道微生物相关研究和认知的不断深入,推动利用干预肠道菌群调节肝脏健康作为肝脏流行性疾病预防和治疗策略的时机已经成熟。本案例拟通过讲解“肝脏流行性疾病发展趋势和现状”、“肠道菌群特征与功能”、“肠道菌群影响肝脏健康和疾病的途径和机制”、以及“肠道菌群在诊断和调节肝脏健康/疾病的研究和实践”等四个主题内容,探讨当前肝脏流行性疾病和微生物学的研究前沿态势,进行实验设计,并进一步探讨用于公共健康人群的肝脏流行性疾病的预防和干预的可行性等,以提高学生系统学研流行性疾病和分析设计实验探究的能力等。
Title: Crack the "gain and loss" of bacteria and promote the "harmony and harmony" of entero-liver —— Case study of intestinal flora homeostasis and liver health
Professional Degree Category: Master of Public Health
Specialized fields: Health toxicology
Authors: Zhong-Ning Lin
Affiliation: School of Public Health, Xiamen University
Key words: Liver diseases, Intestinal microorganisms, Intestinal-liver crosstalk, Public health/medical intervention strategies, Experimental design and practice
Abstract
Research and development of public health/medical guidance or intervention strategies for modulating liver health to aid in the social prevention control and treatment of epidemic diseases has become one of the key disciplinary issues that need to be addressed in the current research field of public health medicine. In recent years, with the increasing research and knowledge related to gut microorganisms, the time is ripe to promote the use of intervention of intestinal microorganisms to regulate liver health as a preventive and therapeutic strategy for hepatic pandemic diseases. In this case, we are going to explain the "Trends and current status of hepatic epidemics", "Characteristics and functions of intestinal microorganisms ", "Pathways and mechanisms by which intestinal microorganisms influence liver health and disease", and "The role of intestinal microorganisms in preventing and treating hepatic diseases". The course will cover four topics, including "Research and Practice of Gut microorganisms in Diagnosis and Regulation of Liver Health/Disease", discussing current research trends in liver epidemics and microbiology, designing experiments, and further exploring the feasibility of preventing and intervening in liver epidemics in public health populations. This course is designed to improve students' ability to systematically study and research epidemiological diseases and to analyze and design experimental investigations.
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【案例说明书】